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x^{2}-\frac{16\times 3x^{2}}{4x+16}
Divide 16 by \frac{4x+16}{3x^{2}} by multiplying 16 by the reciprocal of \frac{4x+16}{3x^{2}}.
x^{2}-\frac{48x^{2}}{4x+16}
Multiply 16 and 3 to get 48.
x^{2}-\frac{48x^{2}}{4\left(x+4\right)}
Factor the expressions that are not already factored in \frac{48x^{2}}{4x+16}.
x^{2}-\frac{12x^{2}}{x+4}
Cancel out 4 in both numerator and denominator.
\frac{x^{2}\left(x+4\right)}{x+4}-\frac{12x^{2}}{x+4}
To add or subtract expressions, expand them to make their denominators the same. Multiply x^{2} times \frac{x+4}{x+4}.
\frac{x^{2}\left(x+4\right)-12x^{2}}{x+4}
Since \frac{x^{2}\left(x+4\right)}{x+4} and \frac{12x^{2}}{x+4} have the same denominator, subtract them by subtracting their numerators.
\frac{x^{3}+4x^{2}-12x^{2}}{x+4}
Do the multiplications in x^{2}\left(x+4\right)-12x^{2}.
\frac{x^{3}-8x^{2}}{x+4}
Combine like terms in x^{3}+4x^{2}-12x^{2}.
x^{2}-\frac{16\times 3x^{2}}{4x+16}
Divide 16 by \frac{4x+16}{3x^{2}} by multiplying 16 by the reciprocal of \frac{4x+16}{3x^{2}}.
x^{2}-\frac{48x^{2}}{4x+16}
Multiply 16 and 3 to get 48.
x^{2}-\frac{48x^{2}}{4\left(x+4\right)}
Factor the expressions that are not already factored in \frac{48x^{2}}{4x+16}.
x^{2}-\frac{12x^{2}}{x+4}
Cancel out 4 in both numerator and denominator.
\frac{x^{2}\left(x+4\right)}{x+4}-\frac{12x^{2}}{x+4}
To add or subtract expressions, expand them to make their denominators the same. Multiply x^{2} times \frac{x+4}{x+4}.
\frac{x^{2}\left(x+4\right)-12x^{2}}{x+4}
Since \frac{x^{2}\left(x+4\right)}{x+4} and \frac{12x^{2}}{x+4} have the same denominator, subtract them by subtracting their numerators.
\frac{x^{3}+4x^{2}-12x^{2}}{x+4}
Do the multiplications in x^{2}\left(x+4\right)-12x^{2}.
\frac{x^{3}-8x^{2}}{x+4}
Combine like terms in x^{3}+4x^{2}-12x^{2}.