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-4\left(x^{2}+12x+36\right)+3
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x+6\right)^{2}.
-4x^{2}-48x-144+3
Use the distributive property to multiply -4 by x^{2}+12x+36.
-4x^{2}-48x-141
Add -144 and 3 to get -141.
-4\left(x^{2}+12x+36\right)+3
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x+6\right)^{2}.
-4x^{2}-48x-144+3
Use the distributive property to multiply -4 by x^{2}+12x+36.
-4x^{2}-48x-141
Add -144 and 3 to get -141.