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\frac{\left(x^{3}+8x\right)\left(x^{2}+x-72\right)}{\left(x^{2}-64\right)\left(x^{2}+4x-45\right)}
Divide \frac{x^{3}+8x}{x^{2}-64} by \frac{x^{2}+4x-45}{x^{2}+x-72} by multiplying \frac{x^{3}+8x}{x^{2}-64} by the reciprocal of \frac{x^{2}+4x-45}{x^{2}+x-72}.
\frac{x\left(x-8\right)\left(x+9\right)\left(x^{2}+8\right)}{\left(x-8\right)\left(x-5\right)\left(x+8\right)\left(x+9\right)}
Factor the expressions that are not already factored.
\frac{x\left(x^{2}+8\right)}{\left(x-5\right)\left(x+8\right)}
Cancel out \left(x-8\right)\left(x+9\right) in both numerator and denominator.
\frac{x^{3}+8x}{x^{2}+3x-40}
Expand the expression.
\frac{\left(x^{3}+8x\right)\left(x^{2}+x-72\right)}{\left(x^{2}-64\right)\left(x^{2}+4x-45\right)}
Divide \frac{x^{3}+8x}{x^{2}-64} by \frac{x^{2}+4x-45}{x^{2}+x-72} by multiplying \frac{x^{3}+8x}{x^{2}-64} by the reciprocal of \frac{x^{2}+4x-45}{x^{2}+x-72}.
\frac{x\left(x-8\right)\left(x+9\right)\left(x^{2}+8\right)}{\left(x-8\right)\left(x-5\right)\left(x+8\right)\left(x+9\right)}
Factor the expressions that are not already factored.
\frac{x\left(x^{2}+8\right)}{\left(x-5\right)\left(x+8\right)}
Cancel out \left(x-8\right)\left(x+9\right) in both numerator and denominator.
\frac{x^{3}+8x}{x^{2}+3x-40}
Expand the expression.