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Differentiate w.r.t. x
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5x^{5-1}+4\times 3x^{4-1}+2\left(-44\right)x^{2-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
5x^{4}+4\times 3x^{4-1}+2\left(-44\right)x^{2-1}
Subtract 1 from 5.
5x^{4}+12x^{4-1}+2\left(-44\right)x^{2-1}
Multiply 4 times 3.
5x^{4}+12x^{3}+2\left(-44\right)x^{2-1}
Subtract 1 from 4.
5x^{4}+12x^{3}-88x^{2-1}
Multiply 4 times 3.
5x^{4}+12x^{3}-88x^{1}
Subtract 1 from 2.
5x^{4}+12x^{3}-88x
For any term t, t^{1}=t.