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Differentiate w.r.t. x
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-\frac{1}{2}\times 9x^{-\frac{1}{2}-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-\frac{9}{2}x^{-\frac{1}{2}-1}
Multiply -\frac{1}{2} times 9.
-\frac{9}{2}x^{-\frac{3}{2}}
Subtract 1 from -\frac{1}{2}.