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-4\left(x^{2}-4x+4\right)\left(x^{2}-9\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-2\right)^{2}.
\left(-4x^{2}+16x-16\right)\left(x^{2}-9\right)
Use the distributive property to multiply -4 by x^{2}-4x+4.
-4x^{4}+20x^{2}+16x^{3}-144x+144
Use the distributive property to multiply -4x^{2}+16x-16 by x^{2}-9 and combine like terms.
-4\left(x^{2}-4x+4\right)\left(x^{2}-9\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-2\right)^{2}.
\left(-4x^{2}+16x-16\right)\left(x^{2}-9\right)
Use the distributive property to multiply -4 by x^{2}-4x+4.
-4x^{4}+20x^{2}+16x^{3}-144x+144
Use the distributive property to multiply -4x^{2}+16x-16 by x^{2}-9 and combine like terms.