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-3x\left(x+1\right)\left(x^{2}-8x+16\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-4\right)^{2}.
\left(-3x^{2}-3x\right)\left(x^{2}-8x+16\right)
Use the distributive property to multiply -3x by x+1.
-3x^{4}+21x^{3}-24x^{2}-48x
Use the distributive property to multiply -3x^{2}-3x by x^{2}-8x+16 and combine like terms.
-3x\left(x+1\right)\left(x^{2}-8x+16\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-4\right)^{2}.
\left(-3x^{2}-3x\right)\left(x^{2}-8x+16\right)
Use the distributive property to multiply -3x by x+1.
-3x^{4}+21x^{3}-24x^{2}-48x
Use the distributive property to multiply -3x^{2}-3x by x^{2}-8x+16 and combine like terms.