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-3\left(x^{2}+8x+16\right)+5
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x+4\right)^{2}.
-3x^{2}-24x-48+5
Use the distributive property to multiply -3 by x^{2}+8x+16.
-3x^{2}-24x-43
Add -48 and 5 to get -43.
-3\left(x^{2}+8x+16\right)+5
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x+4\right)^{2}.
-3x^{2}-24x-48+5
Use the distributive property to multiply -3 by x^{2}+8x+16.
-3x^{2}-24x-43
Add -48 and 5 to get -43.