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\left(x^{2}+10x+25\right)\left(x-2\right)\left(x-6\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x+5\right)^{2}.
\left(x^{2}+10x+25\right)\left(x-2\right)\left(x^{2}-12x+36\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-6\right)^{2}.
\left(x^{3}+8x^{2}+5x-50\right)\left(x^{2}-12x+36\right)
Use the distributive property to multiply x^{2}+10x+25 by x-2 and combine like terms.
x^{5}-4x^{4}-55x^{3}+178x^{2}+780x-1800
Use the distributive property to multiply x^{3}+8x^{2}+5x-50 by x^{2}-12x+36 and combine like terms.
\left(x^{2}+10x+25\right)\left(x-2\right)\left(x-6\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x+5\right)^{2}.
\left(x^{2}+10x+25\right)\left(x-2\right)\left(x^{2}-12x+36\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-6\right)^{2}.
\left(x^{3}+8x^{2}+5x-50\right)\left(x^{2}-12x+36\right)
Use the distributive property to multiply x^{2}+10x+25 by x-2 and combine like terms.
x^{5}-4x^{4}-55x^{3}+178x^{2}+780x-1800
Use the distributive property to multiply x^{3}+8x^{2}+5x-50 by x^{2}-12x+36 and combine like terms.