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\left(4x^{2}+20x+25\right)\left(3x+8\right)^{3}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(2x+5\right)^{2}.
\left(4x^{2}+20x+25\right)\left(27x^{3}+216x^{2}+576x+512\right)
Use binomial theorem \left(a+b\right)^{3}=a^{3}+3a^{2}b+3ab^{2}+b^{3} to expand \left(3x+8\right)^{3}.
108x^{5}+1404x^{4}+7299x^{3}+18968x^{2}+24640x+12800
Use the distributive property to multiply 4x^{2}+20x+25 by 27x^{3}+216x^{2}+576x+512 and combine like terms.
\left(4x^{2}+20x+25\right)\left(3x+8\right)^{3}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(2x+5\right)^{2}.
\left(4x^{2}+20x+25\right)\left(27x^{3}+216x^{2}+576x+512\right)
Use binomial theorem \left(a+b\right)^{3}=a^{3}+3a^{2}b+3ab^{2}+b^{3} to expand \left(3x+8\right)^{3}.
108x^{5}+1404x^{4}+7299x^{3}+18968x^{2}+24640x+12800
Use the distributive property to multiply 4x^{2}+20x+25 by 27x^{3}+216x^{2}+576x+512 and combine like terms.