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Differentiate w.r.t. a
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\frac{\mathrm{d}}{\mathrm{d}a}(a^{8}+18a^{4}+16777216)
Calculate 8 to the power of 8 and get 16777216.
8a^{8-1}+4\times 18a^{4-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
8a^{7}+4\times 18a^{4-1}
Subtract 1 from 8.
8a^{7}+72a^{4-1}
Multiply 4 times 18.
8a^{7}+72a^{3}
Subtract 1 from 4.
a^{8}+18a^{4}+16777216
Calculate 8 to the power of 8 and get 16777216.