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3\left(x^{2}-8x+16\right)\left(x^{2}+3\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-4\right)^{2}.
\left(3x^{2}-24x+48\right)\left(x^{2}+3\right)
Use the distributive property to multiply 3 by x^{2}-8x+16.
3x^{4}+57x^{2}-24x^{3}-72x+144
Use the distributive property to multiply 3x^{2}-24x+48 by x^{2}+3 and combine like terms.
3\left(x^{2}-8x+16\right)\left(x^{2}+3\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-4\right)^{2}.
\left(3x^{2}-24x+48\right)\left(x^{2}+3\right)
Use the distributive property to multiply 3 by x^{2}-8x+16.
3x^{4}+57x^{2}-24x^{3}-72x+144
Use the distributive property to multiply 3x^{2}-24x+48 by x^{2}+3 and combine like terms.