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Evaluate
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Differentiate w.r.t. x
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\frac{4x^{2}}{-1}
Cancel out 2xyz in both numerator and denominator.
-4x^{2}
Anything divided by -1 gives its opposite.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{8yz}{-2yz}x^{3-1})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(-4x^{2})
Do the arithmetic.
2\left(-4\right)x^{2-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-8x^{1}
Do the arithmetic.
-8x
For any term t, t^{1}=t.