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Differentiate w.r.t. a
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\frac{8^{1}a^{2}b^{3}}{\left(-2\right)^{1}a^{1}b^{1}}
Use the rules of exponents to simplify the expression.
\frac{8^{1}}{\left(-2\right)^{1}}a^{2-1}b^{3-1}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{8^{1}}{\left(-2\right)^{1}}a^{1}b^{3-1}
Subtract 1 from 2.
\frac{8^{1}}{\left(-2\right)^{1}}ab^{2}
Subtract 1 from 3.
-4ab^{2}
Divide 8 by -2.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{8b^{3}}{-2b}a^{2-1})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}a}(\left(-4b^{2}\right)a^{1})
Do the arithmetic.
\left(-4b^{2}\right)a^{1-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-4b^{2}\right)a^{0}
Do the arithmetic.
\left(-4b^{2}\right)\times 1
For any term t except 0, t^{0}=1.
-4b^{2}
For any term t, t\times 1=t and 1t=t.