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Differentiate w.r.t. x
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\frac{72x}{5}-46\times \frac{x}{3}
Express 72\times \frac{x}{5} as a single fraction.
\frac{72x}{5}-\frac{46x}{3}
Express 46\times \frac{x}{3} as a single fraction.
\frac{3\times 72x}{15}-\frac{5\times 46x}{15}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of 5 and 3 is 15. Multiply \frac{72x}{5} times \frac{3}{3}. Multiply \frac{46x}{3} times \frac{5}{5}.
\frac{3\times 72x-5\times 46x}{15}
Since \frac{3\times 72x}{15} and \frac{5\times 46x}{15} have the same denominator, subtract them by subtracting their numerators.
\frac{216x-230x}{15}
Do the multiplications in 3\times 72x-5\times 46x.
\frac{-14x}{15}
Combine like terms in 216x-230x.