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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(-3x^{4})
Combine 7x^{4} and -10x^{4} to get -3x^{4}.
4\left(-3\right)x^{4-1}
The derivative of ax^{n} is nax^{n-1}.
-12x^{4-1}
Multiply 4 times -3.
-12x^{3}
Subtract 1 from 4.
-3x^{4}
Combine 7x^{4} and -10x^{4} to get -3x^{4}.