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Differentiate w.r.t. x
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6\times \left(\frac{x^{3}z^{4}}{x^{-4}z^{-2}y}\right)^{-1}
Cancel out y^{2} in both numerator and denominator.
6\times \left(\frac{z^{6}x^{7}}{y}\right)^{-1}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
6\times \frac{\left(z^{6}x^{7}\right)^{-1}}{y^{-1}}
To raise \frac{z^{6}x^{7}}{y} to a power, raise both numerator and denominator to the power and then divide.
\frac{6\left(z^{6}x^{7}\right)^{-1}}{y^{-1}}
Express 6\times \frac{\left(z^{6}x^{7}\right)^{-1}}{y^{-1}} as a single fraction.
\frac{6\left(z^{6}\right)^{-1}\left(x^{7}\right)^{-1}}{y^{-1}}
Expand \left(z^{6}x^{7}\right)^{-1}.
\frac{6z^{-6}\left(x^{7}\right)^{-1}}{y^{-1}}
To raise a power to another power, multiply the exponents. Multiply 6 and -1 to get -6.
\frac{6z^{-6}x^{-7}}{y^{-1}}
To raise a power to another power, multiply the exponents. Multiply 7 and -1 to get -7.