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5x^{-5}y^{2}\times 2^{2}\left(x^{-8}\right)^{2}
Expand \left(2x^{-8}\right)^{2}.
5x^{-5}y^{2}\times 2^{2}x^{-16}
To raise a power to another power, multiply the exponents. Multiply -8 and 2 to get -16.
5x^{-5}y^{2}\times 4x^{-16}
Calculate 2 to the power of 2 and get 4.
20x^{-5}y^{2}x^{-16}
Multiply 5 and 4 to get 20.
20x^{-21}y^{2}
To multiply powers of the same base, add their exponents. Add -5 and -16 to get -21.
5x^{-5}y^{2}\times 2^{2}\left(x^{-8}\right)^{2}
Expand \left(2x^{-8}\right)^{2}.
5x^{-5}y^{2}\times 2^{2}x^{-16}
To raise a power to another power, multiply the exponents. Multiply -8 and 2 to get -16.
5x^{-5}y^{2}\times 4x^{-16}
Calculate 2 to the power of 2 and get 4.
20x^{-5}y^{2}x^{-16}
Multiply 5 and 4 to get 20.
20x^{-21}y^{2}
To multiply powers of the same base, add their exponents. Add -5 and -16 to get -21.