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Differentiate w.r.t. x
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2\times 4x^{2-1}+\left(-2\times 2^{n+1}\right)x^{1-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
8x^{2-1}+\left(-2\times 2^{n+1}\right)x^{1-1}
Multiply 2 times 4.
8x^{1}+\left(-2\times 2^{n+1}\right)x^{1-1}
Subtract 1 from 2.
8x^{1}+\left(-4\times 2^{n}\right)x^{0}
Subtract 1 from 1.
8x+\left(-4\times 2^{n}\right)x^{0}
For any term t, t^{1}=t.
8x+\left(-4\times 2^{n}\right)\times 1
For any term t except 0, t^{0}=1.
8x-4\times 2^{n}
For any term t, t\times 1=t and 1t=t.