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Differentiate w.r.t. u
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4\times 4vu^{4-1}+2\times 4vu^{2-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
16vu^{4-1}+2\times 4vu^{2-1}
Multiply 4 times 4v.
16vu^{3}+2\times 4vu^{2-1}
Subtract 1 from 4.
16vu^{3}+8vu^{2-1}
Multiply 2 times 4v.
16vu^{3}+8vu^{1}
Subtract 1 from 2.
16vu^{3}+8vu
For any term t, t^{1}=t.