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Differentiate w.r.t. b
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4^{1}a^{2}b^{4}\times 3^{1}a^{-16}b^{-2}
Use the rules of exponents to simplify the expression.
4^{1}\times 3^{1}a^{2}a^{-16}b^{4}b^{-2}
Use the Commutative Property of Multiplication.
4^{1}\times 3^{1}a^{2-16}b^{4-2}
To multiply powers of the same base, add their exponents.
4^{1}\times 3^{1}a^{-14}b^{4-2}
Add the exponents 2 and -16.
4^{1}\times 3^{1}\times \frac{1}{a^{14}}b^{2}
Add the exponents 4 and -2.
12\times \frac{1}{a^{14}}b^{2}
Multiply 4 times 3.