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Evaluate
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Differentiate w.r.t. R_1
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4R_{1}+7R_{2}\times 5R_{1}-3R_{2}^{2}\times 2-R_{1}
Multiply R_{2} and R_{2} to get R_{2}^{2}.
4R_{1}+35R_{2}R_{1}-3R_{2}^{2}\times 2-R_{1}
Multiply 7 and 5 to get 35.
4R_{1}+35R_{2}R_{1}-6R_{2}^{2}-R_{1}
Multiply 3 and 2 to get 6.
3R_{1}+35R_{2}R_{1}-6R_{2}^{2}
Combine 4R_{1} and -R_{1} to get 3R_{1}.