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4\left(4x^{2}+12x+9\right)-12\left(2x+3\right)+5
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(2x+3\right)^{2}.
16x^{2}+48x+36-12\left(2x+3\right)+5
Use the distributive property to multiply 4 by 4x^{2}+12x+9.
16x^{2}+48x+36-24x-36+5
Use the distributive property to multiply -12 by 2x+3.
16x^{2}+24x+36-36+5
Combine 48x and -24x to get 24x.
16x^{2}+24x+5
Subtract 36 from 36 to get 0.
4\left(4x^{2}+12x+9\right)-12\left(2x+3\right)+5
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(2x+3\right)^{2}.
16x^{2}+48x+36-12\left(2x+3\right)+5
Use the distributive property to multiply 4 by 4x^{2}+12x+9.
16x^{2}+48x+36-24x-36+5
Use the distributive property to multiply -12 by 2x+3.
16x^{2}+24x+36-36+5
Combine 48x and -24x to get 24x.
16x^{2}+24x+5
Subtract 36 from 36 to get 0.