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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(16x^{6})
Calculate 4 to the power of 2 and get 16.
6\times 16x^{6-1}
The derivative of ax^{n} is nax^{n-1}.
96x^{6-1}
Multiply 6 times 16.
96x^{5}
Subtract 1 from 6.
16x^{6}
Calculate 4 to the power of 2 and get 16.