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\frac{1}{256}\times 49^{2}\times 5^{-3}+\left(-3^{-1}+2^{-2}\right)^{-1}
Calculate 4 to the power of -4 and get \frac{1}{256}.
\frac{1}{256}\times 2401\times 5^{-3}+\left(-3^{-1}+2^{-2}\right)^{-1}
Calculate 49 to the power of 2 and get 2401.
\frac{2401}{256}\times 5^{-3}+\left(-3^{-1}+2^{-2}\right)^{-1}
Multiply \frac{1}{256} and 2401 to get \frac{2401}{256}.
\frac{2401}{256}\times \frac{1}{125}+\left(-3^{-1}+2^{-2}\right)^{-1}
Calculate 5 to the power of -3 and get \frac{1}{125}.
\frac{2401}{32000}+\left(-3^{-1}+2^{-2}\right)^{-1}
Multiply \frac{2401}{256} and \frac{1}{125} to get \frac{2401}{32000}.
\frac{2401}{32000}+\left(-\frac{1}{3}+2^{-2}\right)^{-1}
Calculate 3 to the power of -1 and get \frac{1}{3}.
\frac{2401}{32000}+\left(-\frac{1}{3}+\frac{1}{4}\right)^{-1}
Calculate 2 to the power of -2 and get \frac{1}{4}.
\frac{2401}{32000}+\left(-\frac{1}{12}\right)^{-1}
Add -\frac{1}{3} and \frac{1}{4} to get -\frac{1}{12}.
\frac{2401}{32000}-12
Calculate -\frac{1}{12} to the power of -1 and get -12.
-\frac{381599}{32000}
Subtract 12 from \frac{2401}{32000} to get -\frac{381599}{32000}.