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Differentiate w.r.t. x
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7\times 3x^{7-1}-10x^{1-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
21x^{7-1}-10x^{1-1}
Multiply 7 times 3.
21x^{6}-10x^{1-1}
Subtract 1 from 7.
21x^{6}-10x^{0}
Subtract 1 from 1.
21x^{6}-10
For any term t except 0, t^{0}=1.