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Evaluate
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Differentiate w.r.t. x
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\frac{288^{1}x^{6}y^{10}}{\left(-6\right)^{1}x^{1}y^{4}}
Use the rules of exponents to simplify the expression.
\frac{288^{1}}{\left(-6\right)^{1}}x^{6-1}y^{10-4}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{288^{1}}{\left(-6\right)^{1}}x^{5}y^{10-4}
Subtract 1 from 6.
\frac{288^{1}}{\left(-6\right)^{1}}x^{5}y^{6}
Subtract 4 from 10.
-48x^{5}y^{6}
Divide 288 by -6.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{288y^{10}}{-6y^{4}}x^{6-1})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\left(-48y^{6}\right)x^{5})
Do the arithmetic.
5\left(-48y^{6}\right)x^{5-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-240y^{6}\right)x^{4}
Do the arithmetic.