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-16-18-2\left(-2\right)\times 4\left(-4+\frac{2\times 10}{-6}+5\left(-8\right)\right)\left(-4\right)
Multiply 2 and -8 to get -16. Multiply 3 and -6 to get -18.
-34-2\left(-2\right)\times 4\left(-4+\frac{2\times 10}{-6}+5\left(-8\right)\right)\left(-4\right)
Subtract 18 from -16 to get -34.
-34-\left(-4\times 4\left(-4+\frac{2\times 10}{-6}+5\left(-8\right)\right)\left(-4\right)\right)
Multiply 2 and -2 to get -4.
-34-\left(-16\left(-4+\frac{2\times 10}{-6}+5\left(-8\right)\right)\left(-4\right)\right)
Multiply -4 and 4 to get -16.
-34-\left(-16\left(-4+\frac{20}{-6}+5\left(-8\right)\right)\left(-4\right)\right)
Multiply 2 and 10 to get 20.
-34-\left(-16\left(-4-\frac{10}{3}+5\left(-8\right)\right)\left(-4\right)\right)
Reduce the fraction \frac{20}{-6} to lowest terms by extracting and canceling out 2.
-34-\left(-16\left(-\frac{12}{3}-\frac{10}{3}+5\left(-8\right)\right)\left(-4\right)\right)
Convert -4 to fraction -\frac{12}{3}.
-34-\left(-16\left(\frac{-12-10}{3}+5\left(-8\right)\right)\left(-4\right)\right)
Since -\frac{12}{3} and \frac{10}{3} have the same denominator, subtract them by subtracting their numerators.
-34-\left(-16\left(-\frac{22}{3}+5\left(-8\right)\right)\left(-4\right)\right)
Subtract 10 from -12 to get -22.
-34-\left(-16\left(-\frac{22}{3}-40\right)\left(-4\right)\right)
Multiply 5 and -8 to get -40.
-34-\left(-16\left(-\frac{22}{3}-\frac{120}{3}\right)\left(-4\right)\right)
Convert 40 to fraction \frac{120}{3}.
-34-\left(-16\times \frac{-22-120}{3}\left(-4\right)\right)
Since -\frac{22}{3} and \frac{120}{3} have the same denominator, subtract them by subtracting their numerators.
-34-\left(-16\left(-\frac{142}{3}\right)\left(-4\right)\right)
Subtract 120 from -22 to get -142.
-34-\frac{-16\left(-142\right)}{3}\left(-4\right)
Express -16\left(-\frac{142}{3}\right) as a single fraction.
-34-\frac{2272}{3}\left(-4\right)
Multiply -16 and -142 to get 2272.
-34-\frac{2272\left(-4\right)}{3}
Express \frac{2272}{3}\left(-4\right) as a single fraction.
-34-\frac{-9088}{3}
Multiply 2272 and -4 to get -9088.
-34-\left(-\frac{9088}{3}\right)
Fraction \frac{-9088}{3} can be rewritten as -\frac{9088}{3} by extracting the negative sign.
-34+\frac{9088}{3}
The opposite of -\frac{9088}{3} is \frac{9088}{3}.
-\frac{102}{3}+\frac{9088}{3}
Convert -34 to fraction -\frac{102}{3}.
\frac{-102+9088}{3}
Since -\frac{102}{3} and \frac{9088}{3} have the same denominator, add them by adding their numerators.
\frac{8986}{3}
Add -102 and 9088 to get 8986.