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Differentiate w.r.t. a
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2a^{6}\left(-a^{2}\right)\left(-5\right)
To multiply powers of the same base, add their exponents. Add 5 and 1 to get 6.
-10a^{6}\left(-a^{2}\right)
Multiply 2 and -5 to get -10.
10a^{6}a^{2}
Multiply -10 and -1 to get 10.
10a^{8}
To multiply powers of the same base, add their exponents. Add 6 and 2 to get 8.
\frac{\mathrm{d}}{\mathrm{d}a}(2a^{6}\left(-a^{2}\right)\left(-5\right))
To multiply powers of the same base, add their exponents. Add 5 and 1 to get 6.
\frac{\mathrm{d}}{\mathrm{d}a}(-10a^{6}\left(-a^{2}\right))
Multiply 2 and -5 to get -10.
\frac{\mathrm{d}}{\mathrm{d}a}(10a^{6}a^{2})
Multiply -10 and -1 to get 10.
\frac{\mathrm{d}}{\mathrm{d}a}(10a^{8})
To multiply powers of the same base, add their exponents. Add 6 and 2 to get 8.
8\times 10a^{8-1}
The derivative of ax^{n} is nax^{n-1}.
80a^{8-1}
Multiply 8 times 10.
80a^{7}
Subtract 1 from 8.