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\left(4x-10y\right)\left(3x+4y\right)-6\left(2x-5y\right)\left(x-y\right)
Use the distributive property to multiply 2 by 2x-5y.
12x^{2}+16xy-30yx-40y^{2}-6\left(2x-5y\right)\left(x-y\right)
Apply the distributive property by multiplying each term of 4x-10y by each term of 3x+4y.
12x^{2}-14xy-40y^{2}-6\left(2x-5y\right)\left(x-y\right)
Combine 16xy and -30yx to get -14xy.
12x^{2}-14xy-40y^{2}+\left(-12x+30y\right)\left(x-y\right)
Use the distributive property to multiply -6 by 2x-5y.
12x^{2}-14xy-40y^{2}-12x^{2}+12xy+30yx-30y^{2}
Apply the distributive property by multiplying each term of -12x+30y by each term of x-y.
12x^{2}-14xy-40y^{2}-12x^{2}+42xy-30y^{2}
Combine 12xy and 30yx to get 42xy.
-14xy-40y^{2}+42xy-30y^{2}
Combine 12x^{2} and -12x^{2} to get 0.
28xy-40y^{2}-30y^{2}
Combine -14xy and 42xy to get 28xy.
28xy-70y^{2}
Combine -40y^{2} and -30y^{2} to get -70y^{2}.
\left(4x-10y\right)\left(3x+4y\right)-6\left(2x-5y\right)\left(x-y\right)
Use the distributive property to multiply 2 by 2x-5y.
12x^{2}+16xy-30yx-40y^{2}-6\left(2x-5y\right)\left(x-y\right)
Apply the distributive property by multiplying each term of 4x-10y by each term of 3x+4y.
12x^{2}-14xy-40y^{2}-6\left(2x-5y\right)\left(x-y\right)
Combine 16xy and -30yx to get -14xy.
12x^{2}-14xy-40y^{2}+\left(-12x+30y\right)\left(x-y\right)
Use the distributive property to multiply -6 by 2x-5y.
12x^{2}-14xy-40y^{2}-12x^{2}+12xy+30yx-30y^{2}
Apply the distributive property by multiplying each term of -12x+30y by each term of x-y.
12x^{2}-14xy-40y^{2}-12x^{2}+42xy-30y^{2}
Combine 12xy and 30yx to get 42xy.
-14xy-40y^{2}+42xy-30y^{2}
Combine 12x^{2} and -12x^{2} to get 0.
28xy-40y^{2}-30y^{2}
Combine -14xy and 42xy to get 28xy.
28xy-70y^{2}
Combine -40y^{2} and -30y^{2} to get -70y^{2}.