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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(22x^{e})
Multiply 2 and 11 to get 22.
e\times 22x^{e-1}
The derivative of ax^{n} is nax^{n-1}.
22ex^{e-1}
Multiply e times 22.