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16\left(x^{2}+2xy+y^{2}\right)-25\left(x-y\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x+y\right)^{2}.
16x^{2}+32xy+16y^{2}-25\left(x-y\right)^{2}
Use the distributive property to multiply 16 by x^{2}+2xy+y^{2}.
16x^{2}+32xy+16y^{2}-25\left(x^{2}-2xy+y^{2}\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-y\right)^{2}.
16x^{2}+32xy+16y^{2}-25x^{2}+50xy-25y^{2}
Use the distributive property to multiply -25 by x^{2}-2xy+y^{2}.
-9x^{2}+32xy+16y^{2}+50xy-25y^{2}
Combine 16x^{2} and -25x^{2} to get -9x^{2}.
-9x^{2}+82xy+16y^{2}-25y^{2}
Combine 32xy and 50xy to get 82xy.
-9x^{2}+82xy-9y^{2}
Combine 16y^{2} and -25y^{2} to get -9y^{2}.
16\left(x^{2}+2xy+y^{2}\right)-25\left(x-y\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(x+y\right)^{2}.
16x^{2}+32xy+16y^{2}-25\left(x-y\right)^{2}
Use the distributive property to multiply 16 by x^{2}+2xy+y^{2}.
16x^{2}+32xy+16y^{2}-25\left(x^{2}-2xy+y^{2}\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-y\right)^{2}.
16x^{2}+32xy+16y^{2}-25x^{2}+50xy-25y^{2}
Use the distributive property to multiply -25 by x^{2}-2xy+y^{2}.
-9x^{2}+32xy+16y^{2}+50xy-25y^{2}
Combine 16x^{2} and -25x^{2} to get -9x^{2}.
-9x^{2}+82xy+16y^{2}-25y^{2}
Combine 32xy and 50xy to get 82xy.
-9x^{2}+82xy-9y^{2}
Combine 16y^{2} and -25y^{2} to get -9y^{2}.