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16\left(4x^{2}+4x+1\right)-9\left(x-2\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(2x+1\right)^{2}.
64x^{2}+64x+16-9\left(x-2\right)^{2}
Use the distributive property to multiply 16 by 4x^{2}+4x+1.
64x^{2}+64x+16-9\left(x^{2}-4x+4\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-2\right)^{2}.
64x^{2}+64x+16-9x^{2}+36x-36
Use the distributive property to multiply -9 by x^{2}-4x+4.
55x^{2}+64x+16+36x-36
Combine 64x^{2} and -9x^{2} to get 55x^{2}.
55x^{2}+100x+16-36
Combine 64x and 36x to get 100x.
55x^{2}+100x-20
Subtract 36 from 16 to get -20.
16\left(4x^{2}+4x+1\right)-9\left(x-2\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(2x+1\right)^{2}.
64x^{2}+64x+16-9\left(x-2\right)^{2}
Use the distributive property to multiply 16 by 4x^{2}+4x+1.
64x^{2}+64x+16-9\left(x^{2}-4x+4\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(x-2\right)^{2}.
64x^{2}+64x+16-9x^{2}+36x-36
Use the distributive property to multiply -9 by x^{2}-4x+4.
55x^{2}+64x+16+36x-36
Combine 64x^{2} and -9x^{2} to get 55x^{2}.
55x^{2}+100x+16-36
Combine 64x and 36x to get 100x.
55x^{2}+100x-20
Subtract 36 from 16 to get -20.