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16\left(4p^{2}-12pq+9q^{2}\right)-4\left(2p-3q\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(2p-3q\right)^{2}.
64p^{2}-192pq+144q^{2}-4\left(2p-3q\right)
Use the distributive property to multiply 16 by 4p^{2}-12pq+9q^{2}.
64p^{2}-192pq+144q^{2}-8p+12q
Use the distributive property to multiply -4 by 2p-3q.
16\left(4p^{2}-12pq+9q^{2}\right)-4\left(2p-3q\right)
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(2p-3q\right)^{2}.
64p^{2}-192pq+144q^{2}-4\left(2p-3q\right)
Use the distributive property to multiply 16 by 4p^{2}-12pq+9q^{2}.
64p^{2}-192pq+144q^{2}-8p+12q
Use the distributive property to multiply -4 by 2p-3q.