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Differentiate w.r.t. x_241
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\begin{array}{c}\phantom{\times99}1545\\\underline{\times\phantom{999}241}\\\end{array}
First line up the numbers vertically and match the places from the right like this.
\begin{array}{c}\phantom{\times99}1545\\\underline{\times\phantom{999}241}\\\phantom{\times99}1545\\\end{array}
Now multiply the first number with the 1^{st} digit in 2^{nd} number to get intermediate results. That is Multiply 1545 with 1. Write the result 1545 at the end leaving 0 spaces to the right like this.
\begin{array}{c}\phantom{\times99}1545\\\underline{\times\phantom{999}241}\\\phantom{\times99}1545\\\phantom{\times9}6180\phantom{9}\\\end{array}
Now multiply the first number with the 2^{nd} digit in 2^{nd} number to get intermediate results. That is Multiply 1545 with 4. Write the result 6180 at the end leaving 1 spaces to the right like this.
\begin{array}{c}\phantom{\times99}1545\\\underline{\times\phantom{999}241}\\\phantom{\times99}1545\\\phantom{\times9}6180\phantom{9}\\\underline{\phantom{\times}3090\phantom{99}}\\\end{array}
Now multiply the first number with the 3^{rd} digit in 2^{nd} number to get intermediate results. That is Multiply 1545 with 2. Write the result 3090 at the end leaving 2 spaces to the right like this.
\begin{array}{c}\phantom{\times99}1545\\\underline{\times\phantom{999}241}\\\phantom{\times99}1545\\\phantom{\times9}6180\phantom{9}\\\underline{\phantom{\times}3090\phantom{99}}\\\phantom{\times}372345\end{array}
Now add the intermediate results to get final answer.
1545x_{241}^{1-1}
The derivative of ax^{n} is nax^{n-1}.
1545x_{241}^{0}
Subtract 1 from 1.
1545\times 1
For any term t except 0, t^{0}=1.
1545
For any term t, t\times 1=t and 1t=t.