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Differentiate w.r.t. x_4544
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\begin{array}{c}\phantom{\times999}15262\\\underline{\times\phantom{9999}4544}\\\end{array}
First line up the numbers vertically and match the places from the right like this.
\begin{array}{c}\phantom{\times999}15262\\\underline{\times\phantom{9999}4544}\\\phantom{\times999}61048\\\end{array}
Now multiply the first number with the 1^{st} digit in 2^{nd} number to get intermediate results. That is Multiply 15262 with 4. Write the result 61048 at the end leaving 0 spaces to the right like this.
\begin{array}{c}\phantom{\times999}15262\\\underline{\times\phantom{9999}4544}\\\phantom{\times999}61048\\\phantom{\times99}61048\phantom{9}\\\end{array}
Now multiply the first number with the 2^{nd} digit in 2^{nd} number to get intermediate results. That is Multiply 15262 with 4. Write the result 61048 at the end leaving 1 spaces to the right like this.
\begin{array}{c}\phantom{\times999}15262\\\underline{\times\phantom{9999}4544}\\\phantom{\times999}61048\\\phantom{\times99}61048\phantom{9}\\\phantom{\times9}76310\phantom{99}\\\end{array}
Now multiply the first number with the 3^{rd} digit in 2^{nd} number to get intermediate results. That is Multiply 15262 with 5. Write the result 76310 at the end leaving 2 spaces to the right like this.
\begin{array}{c}\phantom{\times999}15262\\\underline{\times\phantom{9999}4544}\\\phantom{\times999}61048\\\phantom{\times99}61048\phantom{9}\\\phantom{\times9}76310\phantom{99}\\\underline{\phantom{\times}61048\phantom{999}}\\\end{array}
Now multiply the first number with the 4^{th} digit in 2^{nd} number to get intermediate results. That is Multiply 15262 with 4. Write the result 61048 at the end leaving 3 spaces to the right like this.
\begin{array}{c}\phantom{\times999}15262\\\underline{\times\phantom{9999}4544}\\\phantom{\times999}61048\\\phantom{\times99}61048\phantom{9}\\\phantom{\times9}76310\phantom{99}\\\underline{\phantom{\times}61048\phantom{999}}\\\phantom{\times}69350528\end{array}
Now add the intermediate results to get final answer.
15262x_{4544}^{1-1}
The derivative of ax^{n} is nax^{n-1}.
15262x_{4544}^{0}
Subtract 1 from 1.
15262\times 1
For any term t except 0, t^{0}=1.
15262
For any term t, t\times 1=t and 1t=t.