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15\left(4x^{2}-12xy+9y^{2}\right)-4\left(4x-6y\right)-16
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(2x-3y\right)^{2}.
60x^{2}-180xy+135y^{2}-4\left(4x-6y\right)-16
Use the distributive property to multiply 15 by 4x^{2}-12xy+9y^{2}.
60x^{2}-180xy+135y^{2}-16x+24y-16
Use the distributive property to multiply -4 by 4x-6y.
15\left(4x^{2}-12xy+9y^{2}\right)-4\left(4x-6y\right)-16
Use binomial theorem \left(a-b\right)^{2}=a^{2}-2ab+b^{2} to expand \left(2x-3y\right)^{2}.
60x^{2}-180xy+135y^{2}-4\left(4x-6y\right)-16
Use the distributive property to multiply 15 by 4x^{2}-12xy+9y^{2}.
60x^{2}-180xy+135y^{2}-16x+24y-16
Use the distributive property to multiply -4 by 4x-6y.