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Evaluate
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Differentiate w.r.t. x
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100x\times 24736e^{\left(-a_{0}\right)\times 0x+22}
Subtract 3452 from 28188 to get 24736.
2473600xe^{\left(-a_{0}\right)\times 0x+22}
Multiply 100 and 24736 to get 2473600.
2473600xe^{0+22}
Anything times zero gives zero.
2473600xe^{22}
Add 0 and 22 to get 22.