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100k^{2}b^{2}-4\left(5k^{2}+4\right)\left(5b^{2}-20\right)
Multiply -1 and 4 to get -4.
100k^{2}b^{2}+\left(-20k^{2}-16\right)\left(5b^{2}-20\right)
Use the distributive property to multiply -4 by 5k^{2}+4.
100k^{2}b^{2}-100k^{2}b^{2}+400k^{2}-80b^{2}+320
Use the distributive property to multiply -20k^{2}-16 by 5b^{2}-20.
400k^{2}-80b^{2}+320
Combine 100k^{2}b^{2} and -100k^{2}b^{2} to get 0.
100k^{2}b^{2}-4\left(5k^{2}+4\right)\left(5b^{2}-20\right)
Multiply -1 and 4 to get -4.
100k^{2}b^{2}+\left(-20k^{2}-16\right)\left(5b^{2}-20\right)
Use the distributive property to multiply -4 by 5k^{2}+4.
100k^{2}b^{2}-100k^{2}b^{2}+400k^{2}-80b^{2}+320
Use the distributive property to multiply -20k^{2}-16 by 5b^{2}-20.
400k^{2}-80b^{2}+320
Combine 100k^{2}b^{2} and -100k^{2}b^{2} to get 0.