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Evaluate
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Differentiate w.r.t. x
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10x^{18}\left(-\frac{1}{2}\right)y^{3}
To multiply powers of the same base, add their exponents. Add 15 and 3 to get 18.
-5x^{18}y^{3}
Multiply 10 and -\frac{1}{2} to get -5.