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1-\frac{100000\times 119622220865480194561963161495657715064383733760000000000\times 10!}{50!\times 5!}
The factorial of 45 is 119622220865480194561963161495657715064383733760000000000.
1-\frac{11962222086548019456196316149565771506438373376000000000000000\times 10!}{50!\times 5!}
Multiply 100000 and 119622220865480194561963161495657715064383733760000000000 to get 11962222086548019456196316149565771506438373376000000000000000.
1-\frac{11962222086548019456196316149565771506438373376000000000000000\times 3628800}{50!\times 5!}
The factorial of 10 is 3628800.
1-\frac{43408511507665453002645192043544271642563569306828800000000000000000}{50!\times 5!}
Multiply 11962222086548019456196316149565771506438373376000000000000000 and 3628800 to get 43408511507665453002645192043544271642563569306828800000000000000000.
1-\frac{43408511507665453002645192043544271642563569306828800000000000000000}{30414093201713378043612608166064768844377641568960512000000000000\times 5!}
The factorial of 50 is 30414093201713378043612608166064768844377641568960512000000000000.
1-\frac{43408511507665453002645192043544271642563569306828800000000000000000}{30414093201713378043612608166064768844377641568960512000000000000\times 120}
The factorial of 5 is 120.
1-\frac{43408511507665453002645192043544271642563569306828800000000000000000}{3649691184205605365233512979927772261325316988275261440000000000000}
Multiply 30414093201713378043612608166064768844377641568960512000000000000 and 120 to get 3649691184205605365233512979927772261325316988275261440000000000000.
1-\frac{90000}{7567}
Reduce the fraction \frac{43408511507665453002645192043544271642563569306828800000000000000000}{3649691184205605365233512979927772261325316988275261440000000000000} to lowest terms by extracting and canceling out 482316794529616144473835467150491907139595214520320000000000000.
\frac{7567}{7567}-\frac{90000}{7567}
Convert 1 to fraction \frac{7567}{7567}.
\frac{7567-90000}{7567}
Since \frac{7567}{7567} and \frac{90000}{7567} have the same denominator, subtract them by subtracting their numerators.
-\frac{82433}{7567}
Subtract 90000 from 7567 to get -82433.