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Differentiate w.r.t. x
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-5\times \frac{1}{12}x^{9}y^{6}
Reduce the fraction \frac{2}{24} to lowest terms by extracting and canceling out 2.
-\frac{5}{12}x^{9}y^{6}
Multiply -5 and \frac{1}{12} to get -\frac{5}{12}.