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\frac{-288\times 35}{72}+\left(10625-\frac{5}{12}\right)\left(-16\right)
Express -288\times \frac{35}{72} as a single fraction.
\frac{-10080}{72}+\left(10625-\frac{5}{12}\right)\left(-16\right)
Multiply -288 and 35 to get -10080.
-140+\left(10625-\frac{5}{12}\right)\left(-16\right)
Divide -10080 by 72 to get -140.
-140+\left(\frac{127500}{12}-\frac{5}{12}\right)\left(-16\right)
Convert 10625 to fraction \frac{127500}{12}.
-140+\frac{127500-5}{12}\left(-16\right)
Since \frac{127500}{12} and \frac{5}{12} have the same denominator, subtract them by subtracting their numerators.
-140+\frac{127495}{12}\left(-16\right)
Subtract 5 from 127500 to get 127495.
-140+\frac{127495\left(-16\right)}{12}
Express \frac{127495}{12}\left(-16\right) as a single fraction.
-140+\frac{-2039920}{12}
Multiply 127495 and -16 to get -2039920.
-140-\frac{509980}{3}
Reduce the fraction \frac{-2039920}{12} to lowest terms by extracting and canceling out 4.
-\frac{420}{3}-\frac{509980}{3}
Convert -140 to fraction -\frac{420}{3}.
\frac{-420-509980}{3}
Since -\frac{420}{3} and \frac{509980}{3} have the same denominator, subtract them by subtracting their numerators.
-\frac{510400}{3}
Subtract 509980 from -420 to get -510400.