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\left(-y\right)x^{2}z^{3}\times \left(4\times 1z\right)^{2}
Calculate y to the power of 0 and get 1.
\left(-y\right)x^{2}z^{3}\times \left(4z\right)^{2}
Multiply 4 and 1 to get 4.
\left(-y\right)x^{2}z^{3}\times 4^{2}z^{2}
Expand \left(4z\right)^{2}.
\left(-y\right)x^{2}z^{3}\times 16z^{2}
Calculate 4 to the power of 2 and get 16.
\left(-y\right)x^{2}z^{5}\times 16
To multiply powers of the same base, add their exponents. Add 3 and 2 to get 5.
-16yx^{2}z^{5}
Multiply -1 and 16 to get -16.
\left(-y\right)x^{2}z^{3}\times \left(4\times 1z\right)^{2}
Calculate y to the power of 0 and get 1.
\left(-y\right)x^{2}z^{3}\times \left(4z\right)^{2}
Multiply 4 and 1 to get 4.
\left(-y\right)x^{2}z^{3}\times 4^{2}z^{2}
Expand \left(4z\right)^{2}.
\left(-y\right)x^{2}z^{3}\times 16z^{2}
Calculate 4 to the power of 2 and get 16.
\left(-y\right)x^{2}z^{5}\times 16
To multiply powers of the same base, add their exponents. Add 3 and 2 to get 5.
-16yx^{2}z^{5}
Multiply -1 and 16 to get -16.