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\left(\left(-x\right)x-4\left(-x\right)\right)\left(x+4\right)
Use the distributive property to multiply -x by x-4.
\left(\left(-x\right)x+4x\right)\left(x+4\right)
Multiply -4 and -1 to get 4.
\left(-x\right)x^{2}+4\left(-x\right)x+4x^{2}+16x
Apply the distributive property by multiplying each term of \left(-x\right)x+4x by each term of x+4.
-x^{3}+4\left(-1\right)xx+4x^{2}+16x
To multiply powers of the same base, add their exponents. Add 1 and 2 to get 3.
-x^{3}+4\left(-1\right)x^{2}+4x^{2}+16x
Multiply x and x to get x^{2}.
-x^{3}-4x^{2}+4x^{2}+16x
Multiply 4 and -1 to get -4.
-x^{3}+16x
Combine -4x^{2} and 4x^{2} to get 0.
\left(\left(-x\right)x-4\left(-x\right)\right)\left(x+4\right)
Use the distributive property to multiply -x by x-4.
\left(\left(-x\right)x+4x\right)\left(x+4\right)
Multiply -4 and -1 to get 4.
\left(-x\right)x^{2}+4\left(-x\right)x+4x^{2}+16x
Apply the distributive property by multiplying each term of \left(-x\right)x+4x by each term of x+4.
-x^{3}+4\left(-1\right)xx+4x^{2}+16x
To multiply powers of the same base, add their exponents. Add 1 and 2 to get 3.
-x^{3}+4\left(-1\right)x^{2}+4x^{2}+16x
Multiply x and x to get x^{2}.
-x^{3}-4x^{2}+4x^{2}+16x
Multiply 4 and -1 to get -4.
-x^{3}+16x
Combine -4x^{2} and 4x^{2} to get 0.