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-Q=\frac{6\times 12^{x+2}}{4^{x}\times 18^{x+1}}
The equation is in standard form.
\frac{-Q}{-1}=\frac{48\times 12^{x}}{-72^{x}}
Divide both sides by -1.
Q=\frac{48\times 12^{x}}{-72^{x}}
Dividing by -1 undoes the multiplication by -1.
Q=-48\times \left(\frac{1}{6}\right)^{x}
Divide \frac{48\times 12^{x}}{72^{x}} by -1.