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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(-8x^{3})
Combine 72xy and -72xy to get 0.
3\left(-8\right)x^{3-1}
The derivative of ax^{n} is nax^{n-1}.
-24x^{3-1}
Multiply 3 times -8.
-24x^{2}
Subtract 1 from 3.
-8x^{3}
Combine 72xy and -72xy to get 0.