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-32q^{2}+40q-64+5\left(-q^{2}+5q-10\right)
Use the distributive property to multiply -8 by 4q^{2}-5q+8.
-32q^{2}+40q-64+5\left(-q^{2}\right)+25q-50
Use the distributive property to multiply 5 by -q^{2}+5q-10.
-32q^{2}+65q-64+5\left(-q^{2}\right)-50
Combine 40q and 25q to get 65q.
-32q^{2}+65q-114+5\left(-q^{2}\right)
Subtract 50 from -64 to get -114.
-32q^{2}+65q-114-5q^{2}
Multiply 5 and -1 to get -5.
-37q^{2}+65q-114
Combine -32q^{2} and -5q^{2} to get -37q^{2}.
-32q^{2}+40q-64+5\left(-q^{2}+5q-10\right)
Use the distributive property to multiply -8 by 4q^{2}-5q+8.
-32q^{2}+40q-64+5\left(-q^{2}\right)+25q-50
Use the distributive property to multiply 5 by -q^{2}+5q-10.
-32q^{2}+65q-64+5\left(-q^{2}\right)-50
Combine 40q and 25q to get 65q.
-32q^{2}+65q-114+5\left(-q^{2}\right)
Subtract 50 from -64 to get -114.
-32q^{2}+65q-114-5q^{2}
Multiply 5 and -1 to get -5.
-37q^{2}+65q-114
Combine -32q^{2} and -5q^{2} to get -37q^{2}.