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Evaluate
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Differentiate w.r.t. x
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-4x^{-4}z^{0}
Calculate y to the power of 0 and get 1.
-4x^{-4}
Calculate z to the power of 0 and get 1.
\frac{\mathrm{d}}{\mathrm{d}x}(-4x^{-4}z^{0})
Calculate y to the power of 0 and get 1.
\frac{\mathrm{d}}{\mathrm{d}x}(-4x^{-4})
Calculate z to the power of 0 and get 1.
-4\left(-4\right)x^{-4-1}
The derivative of ax^{n} is nax^{n-1}.
16x^{-4-1}
Multiply -4 times -4.
16x^{-5}
Subtract 1 from -4.