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Differentiate w.r.t. x
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-4x^{1-1}+2\times 8x^{2-1}+3\left(-2\right)x^{3-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-4x^{0}+2\times 8x^{2-1}+3\left(-2\right)x^{3-1}
Subtract 1 from 1.
-4x^{0}+16x^{2-1}+3\left(-2\right)x^{3-1}
Multiply 2 times 8.
-4x^{0}+16x^{1}+3\left(-2\right)x^{3-1}
Subtract 1 from 2.
-4x^{0}+16x^{1}-6x^{3-1}
Multiply 2 times 8.
-4x^{0}+16x^{1}-6x^{2}
Subtract 1 from 3.
-4x^{0}+16x-6x^{2}
For any term t, t^{1}=t.
-4+16x-6x^{2}
For any term t except 0, t^{0}=1.